Primary Peritoneal Carcinoma in a BRCA1/2-negative, PALB2-positive patient

Ryan Kahn; Arlene Garcia-Soto; Rachel Silva-Smith; Andre Pinto; Sophia H L George

doi:10.1016/j.gore.2016.08.001

Primary Peritoneal Carcinoma in a BRCA1/2-negative, PALB2-positive patient

Gynecol Oncol Rep. 2016 Aug 2:17:93-5. doi: 10.1016/j.gore.2016.08.001. eCollection 2016 Aug.

Authors

Ryan Kahn¹, Arlene Garcia-Soto², Rachel Silva-Smith³, Andre Pinto⁴, Sophia H L George⁵

Affiliations

¹ University of Miami, Miller School of Medicine, United States.
² Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of Miami, United States.
³ Department of Genetics, University of Miami, United States.
⁴ University of Miami, Miller School of Medicine, United States; Department of Pathology, Jackson Memorial Hospital, United States.
⁵ University of Miami, Miller School of Medicine, United States; Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of Miami, United States; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, United States.

Abstract

•First reported case of PPC after BSO in a BRCA1/2-negative, PALB2-positive patient•The PALB2 mutation and genetic counseling is discussed•Multi-gene panel testing can benefit prognostic factors and targeted therapy.

Keywords: BRIP1; Low-grade serous carcinoma; PALB2; Primary Peritoneal Carcinoma.

Publication types

Case Reports