Caspase-1 clipping causes complications for α-synuclein

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9958-60. doi: 10.1073/pnas.1610993113. Epub 2016 Aug 22.
No abstract available

MeSH terms

  • Caspase 1 / genetics
  • Caspase 1 / metabolism*
  • Humans
  • Nerve Degeneration / genetics
  • Nerve Degeneration / pathology
  • Neurons / metabolism*
  • Neurons / pathology
  • Parkinson Disease / drug therapy
  • Parkinson Disease / genetics*
  • Parkinson Disease / pathology
  • Protein Aggregation, Pathological / genetics
  • Proteolysis
  • alpha-Synuclein / genetics
  • alpha-Synuclein / metabolism*

Substances

  • alpha-Synuclein
  • Caspase 1