Background and objective: Erythema dyschromicum perstans (EDP) is a cosmetically distressing, acquired pigmentary disorder of unknown etiology for which few successful therapies exist. Herein, we present the successful use of non-ablative fractional photothermolysis in combination with topical tacrolimus ointment.
Study design/patients and methods: A 35-year-old female with biopsy-confirmed EDP underwent a series of fractionated non-ablative treatment sessions utilizing the 1,550 nm erbium-doped fiber laser in combination with topical tacrolimus ointment over a period of 5 months.
Results: The patient's EDP improved by greater than 75% and results were maintained at the 8-month follow-up visit.
Conclusion: The combination of non-ablative fractional photothermolysis and topical tacrolimus ointment is a potential safe and effective therapeutic option for erythema dyschromicum perstans. Additional prospective, comparative studies are warranted. Lasers Surg. Med. 49:60-62, 2017. © 2016 Wiley Periodicals, Inc.
Keywords: ashy dermatosis; edp; erythema dyschromicum perstans; fraxel; laser; nonablative 1550 nm erbium-doped fractionated laser; pigment disorder; pigmentary disorder.
© 2016 Wiley Periodicals, Inc.