Non-contact single shot elastography using line field low coherence holography

Biomed Opt Express. 2016 Jul 12;7(8):3021-31. doi: 10.1364/BOE.7.003021. eCollection 2016 Aug 1.

Abstract

Optical elastic wave imaging is a powerful technique that can quantify local biomechanical properties of tissues. However, typically long acquisition times make this technique unfeasible for clinical use. Here, we demonstrate non-contact single shot elastographic holography using a line-field interferometer integrated with an air-pulse delivery system. The propagation of the air-pulse induced elastic wave was imaged in real time, and required a single excitation for a line-scan measurement. Results on tissue-mimicking phantoms and chicken breast muscle demonstrated the feasibility of this technique for accurate assessment of tissue biomechanical properties with an acquisition time of a few milliseconds using parallel acquisition.

Keywords: (110.4500) Optical coherence tomography; (170.0110) Imaging systems; (170.0170) Medical optics and biotechnology.