Abstract
The effects of 10 ml of evening primrose oil or olive oil, administered twice daily for 12 weeks, on clinical and laboratory signs and on plasma prostaglandins were studied in 18 patients with rheumatoid arthritis. The plasma concentration of PGE2 decreased and that of TxB2 increased in both treatment groups, but no significant improvement could be seen in either group.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Arthritis, Rheumatoid / blood
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Arthritis, Rheumatoid / drug therapy*
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Arthritis, Rheumatoid / physiopathology
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Fatty Acids, Essential / therapeutic use*
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Female
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Humans
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Linoleic Acids
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Male
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Middle Aged
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Oenothera biennis
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Olive Oil
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Osmolar Concentration
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Pain
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Plant Oils / therapeutic use*
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Prostaglandins / blood
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Prostaglandins / urine
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gamma-Linolenic Acid
Substances
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Fatty Acids, Essential
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Linoleic Acids
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Olive Oil
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Plant Oils
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Prostaglandins
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evening primrose oil
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gamma-Linolenic Acid