Development and validation of a new ICD-10-based trauma mortality prediction scoring system using a Japanese national inpatient database

Inj Prev. 2017 Aug;23(4):263-267. doi: 10.1136/injuryprev-2016-042106. Epub 2016 Sep 5.

Abstract

Introduction: To develop and validate a new trauma mortality prediction scoring system based on International Statistical Classification of Diseases (ICD)-10 codes, using a Japanese administrative claims and discharge abstract database.

Methods: This retrospective observational study used the Japanese Diagnosis Procedure Combination database. Injuries were categorised into 33 groups with 5 additional groups based on injury sites and types. A multivariable logistic regression analysis was performed for in-hospital mortality in a derivation cohort after adjusting for the 38 groups, patient's sex, age and Charlson Comorbidity Index score. Each variable was assigned a score that was equal to the value of the regression coefficient. The new severity score was defined as the sum of the scores. The new scoring system was tested in a validation cohort.

Results: The mortality rates were 2.4% (9270/393 395) and 2.5% (8778/349 285) in the derivation and validation cohorts, respectively. The area under the receiver operating curve (AUROC) of the new scoring system was 0.887 (95% CI 0.884 to 0.890) in the validation cohort. Subgroup analyses showed that the scoring system retained high predictive performance both for patients <65 years (AUROC 0.934, 95% CI 0.928 to 0.939) and for elderly patients at the age of ≥65 years (AUROC 0.825, 95% CI 0.820 to 0.829).

Conclusions: A new ICD-10-based injury severity scoring system was developed and validated. Further studies are required to validate the scoring system in other databases.

Publication types

  • Observational Study
  • Validation Study

MeSH terms

  • Adult
  • Aged
  • Comorbidity
  • Databases, Factual
  • Female
  • Hospital Mortality*
  • Humans
  • Injury Severity Score
  • Inpatients / statistics & numerical data*
  • International Classification of Diseases* / trends
  • Japan
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Reproducibility of Results
  • Retrospective Studies
  • Risk Adjustment
  • Wounds and Injuries / classification*
  • Wounds and Injuries / mortality