Multiple meningiomas in a woman irradiated in utero

J Clin Neurosci. 2016 Nov:33:225-227. doi: 10.1016/j.jocn.2016.03.030. Epub 2016 Sep 6.

Abstract

Meningiomas are a common central nervous system tumour and radiation is a known risk factor for their development. In utero radiation exposure correlates to developmental abnormalities and carcinogenesis in a dose- and gestational age-related manner. Radiation induced meningioma has been reported in detail in the literature in patients who had been irradiated earlier in life. At the time of publication, there was no data on radiation exposure whilst in utero and meningioma. We report on a 42-year-old woman with multiple intracranial meningiomas and no other risk factors except a history of in utero exposure to low dose X-ray radiation at 12weeks gestational age.

Keywords: Fetal radiation; In utero radiation; Meningioma; Pregnancy; Radiation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Meningeal Neoplasms / pathology*
  • Meningioma / pathology*
  • Neoplasms, Radiation-Induced / pathology*
  • Pregnancy
  • Prenatal Exposure Delayed Effects / pathology*

Supplementary concepts

  • Radiation induced meningioma