Heart rate reduction may be a major determinant of vascular tone in esmolol-treated septic shock patients-although still remains to be confirmed!

Affiliations

• ¹ Medical Intensive Care Unit and Medico-surgical Cardiology Department, CHU Brabois 54500 Vandoeuvre les Nancy, France;; Shock Group, INSERM U1116, Faculté de Médecine, 54500 Vandoeuvre les Nancy, France;; Lorraine University, 34 Cours Léopold, Nancy, France;
• ² Shock Group, INSERM U1116, Faculté de Médecine, 54500 Vandoeuvre les Nancy, France;; Lorraine University, 34 Cours Léopold, Nancy, France;
• ³ Intensive Care Unit, CHU Raymond Poincaré 92380 Garches, France;; Chronic Infection and Inflammation Laboratory, INSERM U1173, UFR des sciences de la Santé, Batiment Simone Veil, 78180 Montigny-Le-Bretonneux, France;; Versailles Saint Quentin en Yvelines University, 78140 Vélizy-Villacoublay, France.