Watching a deep dive: Live imaging provides lessons about tooth invagination

Amnon Sharir; Ophir D Klein

doi:10.1083/jcb.201608088

Watching a deep dive: Live imaging provides lessons about tooth invagination

J Cell Biol. 2016 Sep 12;214(6):645-7. doi: 10.1083/jcb.201608088.

Authors

Amnon Sharir¹, Ophir D Klein²

Affiliations

¹ Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA 94143 Program in Craniofacial Biology, University of California, San Francisco, San Francisco, CA 94143.
² Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA 94143 Program in Craniofacial Biology, University of California, San Francisco, San Francisco, CA 94143 Department of Pediatrics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 [email protected].

Abstract

Invagination of epithelium into the surrounding mesenchyme is a critical step that marks the developmental onset of many ectodermal organs. In this issue, Ahtiainen et al. (2016. J. Cell. Biol. http://dx.doi.org/10.1083/jcb.201512074) use the mouse incisor as a model to advance our understanding of the cellular mechanisms underlying ectodermal organ morphogenesis.

Publication types

Comment

MeSH terms

Animals
Epithelium*
Mesoderm*
Mice
Organogenesis

Grants and funding

R35 DE026602/DE/NIDCR NIH HHS/United States