Genetic Characterization of a blaVEB-2-Carrying Plasmid in Vibrio parahaemolyticus

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6965-6968. doi: 10.1128/AAC.01749-16. Print 2016 Nov.

Abstract

This report describes the first detection of a blaVEB-2 gene in a Vibrio parahaemolyticus strain isolated from a shrimp sample. The blaVEB-2 gene was carried on a novel Inc-type plasmid that was likely to have originated from aquatic organisms, as indicated by a comparison with other known genetic elements in the GenBank database. However, the plasmid contains resistance elements usually harbored by members of the family Enterobacteriaceae, suggesting that gene transfer events occurred and contributed to the formation of this multidrug resistance-encoding plasmid.

MeSH terms

  • Animals
  • Bacterial Proteins / genetics
  • Cephalosporin Resistance / drug effects
  • Cephalosporin Resistance / genetics*
  • China
  • Crustacea / microbiology
  • Enterobacteriaceae / genetics
  • Integrons
  • Microbial Sensitivity Tests
  • Plasmids / genetics*
  • Vibrio parahaemolyticus / drug effects
  • Vibrio parahaemolyticus / genetics*
  • Vibrio parahaemolyticus / isolation & purification
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • beta-Lactamases