The novel HLA-C*15:103 is characterised by an amino acid substitution in the alpha 2 domain

HLA. 2016 Nov;88(5):267-268. doi: 10.1111/tan.12897. Epub 2016 Sep 20.

Abstract

HLA-C*15:103 allele is characterised by one amino acid substitution in the alpha 2 domain.

Keywords: HLA-C*15; hematopoietic stem cell transplantation; human leukocyte antigen-C; matched unrelated donor; sequence-based typing.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alleles*
  • Amino Acid Substitution
  • Base Sequence
  • Child
  • Codon / chemistry
  • Exons*
  • Female
  • Genotype
  • HLA-C Antigens / genetics*
  • HLA-C Antigens / immunology
  • Hematopoietic Stem Cell Transplantation / methods*
  • Histocompatibility Testing
  • Humans
  • Leukemia / immunology
  • Leukemia / pathology
  • Leukemia / therapy*
  • Male
  • Middle Aged
  • Pedigree
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • Protein Domains
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Treatment Outcome
  • Unrelated Donors*

Substances

  • Codon
  • HLA-C Antigens
  • HLA-C*15 antigen