Molybdenum disulfide nanosheets coated multiwalled carbon nanotubes composite for highly sensitive determination of chloramphenicol in food samples milk, honey and powdered milk

J Colloid Interface Sci. 2017 Jan 1:485:129-136. doi: 10.1016/j.jcis.2016.09.029. Epub 2016 Sep 14.

Abstract

We have described a hybrid material that consists of molybdenum disulfide nanosheets (MoS2) coated on functionalized multiwalled carbon nanotubes (f-MWCNTs) for sensitive and selective determination of chloramphenicol (CAP). The MoS2/f-MWCNTs nanocomposite was successfully prepared through a hydrothermal process and its structure was characterized by scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, electrochemical impedance spectroscopy and cyclic voltammetry. The MoS2/f-MWCNTs nanocomposite holds excellent electrochemical properties and it displays excellent electrocatalytic ability to CAP. Under optimized working conditions, the nanocomposite film modified electrode responds linearly to CAP in the concentration range of 0.08-1392μM. The detection limit was obtained as 0.015μM (±0.003). The electrode has high level of selectivity in presence of large excess concentrations of interfering species. In addition, the modified electrode offers satisfactory repeatability, reproducibility and stability. The practical applicability of the electrode was demonstrated in food samples such as, milk, powdered milk and honey samples and the recoveries are agreeable which clearly revealed its practical feasibility in food analysis.

Keywords: Antibiotics; Electrochemical sensor; Food safety; Hybrid materials; Layered 2D transition metal dichalcogenides; Nanomaterials and nanocomposites; Thin films; Veterinary antibacterial drug.

MeSH terms

  • Animals
  • Chloramphenicol / analysis*
  • Disulfides / chemistry*
  • Electrochemical Techniques
  • Electrodes
  • Food Contamination / analysis
  • Honey / analysis*
  • Limit of Detection
  • Milk / chemistry*
  • Molybdenum / chemistry*
  • Nanocomposites / chemistry*
  • Nanocomposites / ultrastructure
  • Nanotubes, Carbon / chemistry*
  • Nanotubes, Carbon / ultrastructure
  • Powders
  • Reproducibility of Results

Substances

  • Disulfides
  • Nanotubes, Carbon
  • Powders
  • Chloramphenicol
  • Molybdenum
  • molybdenum disulfide