Optimization of breathing instructions and timing of late arterial phase acquisition on gadobutrol-enhanced MRI of the liver

Daniella F Pinho; Naama Lev-Cohain; Haitham Awdeh; Yin Xi; Gaurav Khatri; Takeshi Yokoo; Ivan Pedrosa

doi:10.1016/j.clinimag.2016.08.021

Optimization of breathing instructions and timing of late arterial phase acquisition on gadobutrol-enhanced MRI of the liver

Clin Imaging. 2016 Nov-Dec;40(6):1274-1279. doi: 10.1016/j.clinimag.2016.08.021. Epub 2016 Sep 4.

Authors

Daniella F Pinho¹, Naama Lev-Cohain², Haitham Awdeh³, Yin Xi⁴, Gaurav Khatri⁵, Takeshi Yokoo⁶, Ivan Pedrosa⁷

Affiliations

¹ Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].
² Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].
³ Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].
⁴ Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].
⁵ Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].
⁶ Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].
⁷ Department of Radiology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 210, Dallas, TX 75390-9085. Electronic address: [email protected].

PMID: 27684994
DOI: 10.1016/j.clinimag.2016.08.021

Abstract

Purpose: To compare a protocol with higher concentration macrocyclic gadolinium-based contrast agent (GBCA) [study group] to the traditional protocol with lower-concentration linear GBCAs [control group] for breath-held arterial phase magnetic resonance imaging.

Material and methods: A total of 136 patients were quantitatively evaluated for image quality (IQ), breathing artifacts (BA), and timing of the arterial phase (Tap). Quantitative analysis was also performed.

Results: No significant differences in IQ, BA and Tap (P>.05). Study group exhibited less enhancement of the aorta (P=.0091) and smaller standard deviation for the portal vein enhancement (P=.0173).

Conclusion: Similar arterial-phase image quality can be achieved with a macrocyclic GBCA compared to traditional linear GBCA.

Keywords: Arterial phase; Gadobutrol; Liver; Magnetic resonance imaging.

MeSH terms

Aorta / diagnostic imaging
Artifacts
Breath Holding*
Contrast Media / administration & dosage*
Humans
Image Enhancement / methods*
Liver / diagnostic imaging*
Magnetic Resonance Imaging / methods*
Organometallic Compounds / administration & dosage*
Portal Vein / diagnostic imaging
Retrospective Studies

Substances

Contrast Media
Organometallic Compounds
gadobutrol