Evaluation of Cardiac, Vascular, and Skeletal Muscle Function With MRI: Novel Physiological End Points in Cardiac Rehabilitation Research

Can J Cardiol. 2016 Oct;32(10 Suppl 2):S388-S396. doi: 10.1016/j.cjca.2016.07.006. Epub 2016 Jul 18.

Abstract

Impaired exercise tolerance is a major determinant of decreased quality of life and survival in individuals with cardiovascular disease. The relative contribution that abnormal cardiac, vascular, and skeletal muscle function plays in limiting exercise tolerance and its improvement with exercise training in patients with cardiovascular disease is not fully known. In this review, we provide an overview of the functional impairment of these systems as they relate to exercise capacity and the emerging role of magnetic resonance imaging as a comprehensive tool to evaluate mechanisms that may explain exercise intolerance.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aorta / diagnostic imaging
  • Cardiac Rehabilitation*
  • Cardiovascular Diseases / physiopathology*
  • Exercise Tolerance / physiology
  • Heart / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging*
  • Muscle, Skeletal / blood supply
  • Muscle, Skeletal / diagnostic imaging*
  • Oxygen Consumption / physiology