Screening for Ricinoleic Acid as a Chemical Marker for Secale cornutum in Rye by High-Performance Thin-Layer Chromatography with Fluorescence Detection

J Agric Food Chem. 2016 Nov 2;64(43):8246-8253. doi: 10.1021/acs.jafc.6b03841. Epub 2016 Oct 19.

Abstract

Ricinoleic acid as the characteristic fatty acid of Secale cornutum oil is a good marker for Secale cornutum impurities in cereal. The presented screening for ricinoleic acid in rye by high-performance thin-layer chromatography with fluorescence detection (HPTLC-FLD) offers a selective and sensitive method for the determination of Secale cornutum and is very different from existing gas chromatographic analyses. Lipid extraction was followed by transesterification and solid-phase extraction cleanup; thereafter, extracts were selectively derivatized with 2-naphthoyl chloride and analyzed by HPTLC-FLD with silica gel plates and cyclohexane/diisopropyl ether/formic acid (86:14:1, v/v/v) as mobile phase. For quantitation, the enhanced fluorescence was scanned at 280/>340 nm. Limits of detection and quantitation of 0.1 and 0.4 mg ricinoleic acid/kg of rye were obtained, which enables the determination of Secale cornutum far below the maximum admitted level. With near-100% recoveries and low standard deviations at relevant spiking levels, reliable results were guaranteed.

Keywords: HPTLC−FLD; Secale cornutum; high-performance thin-layer chromatography−fluorescence detection; ricinoleic acid; rye; screening.

MeSH terms

  • Biomarkers / analysis*
  • Biomarkers / chemistry
  • Chromatography, Thin Layer / methods*
  • Fluorescence
  • Food Contamination / analysis
  • Naphthalenes / chemistry
  • Reproducibility of Results
  • Ricinoleic Acids / analysis*
  • Ricinoleic Acids / chemistry
  • Secale / chemistry*
  • Sensitivity and Specificity
  • Solid Phase Extraction / methods

Substances

  • Biomarkers
  • Naphthalenes
  • Ricinoleic Acids
  • 2-naphthoyl chloride
  • ricinoleic acid