The Association of Prenatal Tocolysis and Breastfeeding Duration

Breastfeed Med. 2016 Dec:11:561-563. doi: 10.1089/bfm.2016.0130. Epub 2016 Oct 5.

Abstract

Background: To date there are no clinical studies analyzing potential effects of tocolytics on breastfeeding duration in humans.

Objectives: The purpose of this study was to evaluate the association between beta 2 agonists prescribed for tocolysis during pregnancy and breastfeeding duration.

Methods: We conducted a cross-sectional questionnaire study of 114 mothers and filled in the questionnaire developed to directly address the goals of the study.

Results: There was a statistically significant difference between breastfeeding duration of mothers who were on tocolytics during pregnancy versus those who were not prescribed tocolytics (9.5 ± 5.7 months versus 4.5 ± 2.1 months) p < 0.001. In addition, hypogalactia was statistically significantly more prevalent in mothers with positive history versus mothers with negative history of tocolytic usage p < 0.001.

Conclusion: The results of our study indicate that tocolytic treatment in pregnancy is associated with shorter breastfeeding duration and hypogalactia.

Keywords: breastfeeding duration; lactogenesis; tocolysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Agonists / therapeutic use*
  • Adult
  • Breast Feeding / psychology
  • Breast Feeding / statistics & numerical data*
  • Cross-Sectional Studies
  • Female
  • Fetal Membranes, Premature Rupture / drug therapy
  • Fetal Membranes, Premature Rupture / prevention & control*
  • Humans
  • Mothers / psychology*
  • Mothers / statistics & numerical data
  • Pregnancy
  • Serbia
  • Time Factors
  • Tocolysis / methods*
  • Tocolytic Agents / therapeutic use*

Substances

  • Adrenergic beta-Agonists
  • Tocolytic Agents