Trigeminal neuralgia: a retrospective multicentre study of 320 Asian patients

Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Jan;123(1):51-57. doi: 10.1016/j.oooo.2016.08.005. Epub 2016 Aug 17.

Abstract

Objectives: This study was performed to obtain the clinicodemographic data regarding patients with trigeminal neuralgia (TN) treated at oral-maxillofacial medicine clinics, as there is a paucity of such information in the Asian setting.

Study design: Retrospective multicenter study involving clinicodemographic information of 320 patients with TN diagnosed between 2001 and 2012 at eight regional oral-maxillofacial medicine clinics and followed up for at least 6 months. Statistical tests were performed to assess the associations among the clinicodemographic factors.

Results: TN was mostly diagnosed during the seventh and sixth decades of life, with a median of 58.2 years (interquartile range = 13.0). Females were more commonly affected (61.6%). TN affected the right side more frequently, and the mandibular branch was most commonly involved (58.5%). Carbamazepine was the first-line drug of choice (87.5%).

Conclusions: Asian patients with TN exhibited features similar to those in Caucasian patients except for the increased affliction of the mandibular division.

Publication types

  • Multicenter Study

MeSH terms

  • Analgesics, Non-Narcotic / therapeutic use
  • Carbamazepine / therapeutic use
  • Female
  • Humans
  • Malaysia / epidemiology
  • Male
  • Mandible / innervation
  • Middle Aged
  • Retrospective Studies
  • Sex Factors
  • Treatment Outcome
  • Trigeminal Neuralgia / diagnosis
  • Trigeminal Neuralgia / drug therapy
  • Trigeminal Neuralgia / ethnology*

Substances

  • Analgesics, Non-Narcotic
  • Carbamazepine