Idarucizumab for dabigatran overdose in a child

Br J Haematol. 2018 Feb;180(3):457-459. doi: 10.1111/bjh.14371. Epub 2016 Oct 13.

Authors

Susan Shapiro¹, Neha Bhatnagar², Asif Khan³, James Beavis⁴, David Keeling¹

Affiliations

¹ Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals NHS Foundation Trust, Oxford Comprehensive Biomedical Resource Centre*, Oxford, UK.
² Department of Paediatric Haematology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
³ Department of Haematology, Royal Berkshire Hospital, Reading, UK.
⁴ Haemostasis Laboratory, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

PMID: 27734469
DOI: 10.1111/bjh.14371

No abstract available

Keywords: dabigatran; direct oral anticoagulant; idarucizumab; overdose; reversal.

Publication types

Case Reports
Letter

MeSH terms

Adolescent
Antibodies, Monoclonal, Humanized / pharmacology
Antibodies, Monoclonal, Humanized / therapeutic use*
Anticoagulants / pharmacology
Anticoagulants / therapeutic use*
Antithrombins / administration & dosage
Antithrombins / adverse effects*
Blood Coagulation / drug effects
Blood Coagulation Tests
Dabigatran / administration & dosage
Dabigatran / adverse effects*
Dabigatran / antagonists & inhibitors*
Drug Overdose / blood
Drug Overdose / diagnosis
Drug Overdose / drug therapy*
Female
Humans

Substances

Antibodies, Monoclonal, Humanized
Anticoagulants
Antithrombins
idarucizumab
Dabigatran