We present two results which combined enable one to reliably detect multimode, multipartite entanglement in the presence of measurement errors. The first result leads to a method to compute the best (approximated) physical covariance matrix given a measured nonphysical one assuming that no additional information about the measurement is available except the standard deviations from the mean values. The other result states that a widely used entanglement condition is a consequence of negativity of partial transposition. Our approach can quickly verify the entanglement of experimentally obtained multipartite states, which is demonstrated on several realistic examples. Compared to existing detection schemes, ours is very simple and efficient. In particular, it does not require any complicated optimizations.