Objective: To evaluate the risk factors of full-term infants with low birth weight. Methods: All related Chinese and English literatures published from 1980 to February 25, 2016 were collected from CBM, CNKI, Wang Fang Data, Medline and Embase databases, and screened with inclusion and exclusion criteria and Stata13.0 software was used in this Meta-analysis. Results: Twenty three studies were included and there were 278 020 subjects. Female infants (pooled OR=1.60, 95%CI: 1.49-1.72), less antenatal care visits (pooled OR=1.81, 95%CI: 1.54-2.11), maternal passive smoking (pooled OR=1.49, 95% CI: 1.08-2.06), pregnancy-induced hypertension (pooled OR=2.96, 95% CI: 1.85-4.74) and hypamnion (pooled OR=2.71, 95%CI: 1.87-3.93) were the risk factors for full-term infants with low birth weight. Conclusion: Departments of maternal and health care should encourage pregnant women to have antenatal care visits to find and treat their pregnancy complications, and avoid passive smoking actively through health education for the purpose to prompt the birth quality of infants.