Abstract
Severe fever with thrombocytopenia syndrome is an emerging hemorrhagic fever disease in eastern Asia, caused by a tickborne bunyavirus. Of 25 patients hospitalized with this disease in China, 100% produced and maintained neutralizing antibodies to severe fever with thrombocytopenia syndrome virus for the study period of 4 years.
Keywords:
China; SFTS; SFTSV; bunyavirus; hemorrhagic fever; neutralizing antibodies; plaque assay; severe fever with thrombocytopenia syndrome; severe fever with thrombocytopenia syndrome virus; viruses.
MeSH terms
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Adult
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Aged
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Antibodies, Neutralizing / blood
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Antibodies, Neutralizing / immunology*
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Antibodies, Viral / blood
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Antibodies, Viral / immunology*
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China / epidemiology
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Communicable Diseases, Emerging / epidemiology
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Communicable Diseases, Emerging / immunology
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Communicable Diseases, Emerging / virology
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Enzyme-Linked Immunosorbent Assay
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Female
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Hospitalization*
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Humans
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Male
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Middle Aged
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Neutralization Tests
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Phlebotomus Fever / epidemiology*
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Phlebotomus Fever / immunology*
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Phlebotomus Fever / virology
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Phlebovirus / classification
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Phlebovirus / genetics
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Phlebovirus / immunology*
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RNA, Viral
Substances
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Antibodies, Neutralizing
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Antibodies, Viral
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RNA, Viral