Production and modeling of radioactive gold nanoparticles in Tehran research reactor

Seyedeh Fatemeh Hosseini; Mahdi Sadeghi; Mohammad Reza Aboudzadeh; Morteza Mohseni

doi:10.1016/j.apradiso.2016.10.004

Production and modeling of radioactive gold nanoparticles in Tehran research reactor

Appl Radiat Isot. 2016 Dec:118:361-365. doi: 10.1016/j.apradiso.2016.10.004. Epub 2016 Oct 5.

Authors

Seyedeh Fatemeh Hosseini¹, Mahdi Sadeghi², Mohammad Reza Aboudzadeh³, Morteza Mohseni¹

Affiliations

¹ Department of Physics, Payam-e Noor University, P.O. Box: 19395-3697, Tehran, Iran.
² Radiation Application Research School, Nuclear Science and Technology Research Institute, P.O. Box: 11365-8486, Tehran, Iran. Electronic address: [email protected].
³ Radiation Application Research School, Nuclear Science and Technology Research Institute, P.O. Box: 11365-8486, Tehran, Iran.

PMID: 27771447
DOI: 10.1016/j.apradiso.2016.10.004

Abstract

Gold has two medically useful radioactive isotopes, ¹⁹⁸Au and ¹⁹⁹Au, for locally irradiating and killing tumor cells. ¹⁹⁸Au radionuclide has been produced through the irradiation of the pure gold via ¹⁹⁷Au(n,γ)¹⁹⁸Au reaction in the Tehran Research Reactor at a thermal neutron flux of 4.5×10¹³ncm^-2s^-1 for the different irradiation times. In this paper, the activity of ¹⁹⁸Au radionuclide has been determined using MCNPX-2.6 and TALYS-1.6 codes and also the theoretical approach. The calculated results were compared with the corresponding experimental values. The calculated results were in good agreement with the experimental data, thus the used codes can be used as a powerful tool to predict and optimize production conditions in reactor.

Keywords: Activity; Gold radionuclide; Monte Carlo; Reactor core.