Abstract
NCRC11 is a monoclonal antibody raised against human mammary carcinoma cells. The prognostic value of tumour cell immunoreactivity to NCRC11 in breast cancer has been shown previously. This study describes NCRC11 immunoreactivity in a wide range of normal and neoplastic epithelial types from the female genital tract and ovary. In the tumours examined, a wide range of staining patterns was seen. The implications of these findings are discussed in relation to the potential uses of this antibody in diagnosis and monitoring of gynaecological diseases.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Monoclonal / immunology*
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Antigens, Neoplasm / immunology
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Brenner Tumor / immunology
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Brenner Tumor / pathology
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Endometrium / cytology
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Endometrium / immunology
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Endometrium / pathology
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Epithelial Cells
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Epithelium / immunology
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Epithelium / pathology
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Female
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Genital Neoplasms, Female / diagnosis
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Genital Neoplasms, Female / immunology*
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Genital Neoplasms, Female / pathology
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Genitalia, Female / cytology
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Genitalia, Female / immunology*
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Humans
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Ovarian Neoplasms / diagnosis
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Ovarian Neoplasms / immunology*
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Ovarian Neoplasms / pathology
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Ovary / cytology
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Ovary / immunology*
Substances
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Antibodies, Monoclonal
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Antigens, Neoplasm