Effectiveness, efficiency and efficacy in the multidimensional treatment of schizophrenia: Rethinking project

Rev Psiquiatr Salud Ment. 2017 Jan-Mar;10(1):4-20. doi: 10.1016/j.rpsm.2016.09.001. Epub 2016 Oct 22.
[Article in English, Spanish]

Abstract

Schizophrenia is a clinically heterogeneous syndrome affecting multiple dimensions of patients' life. Therefore, its treatment might require a multidimensional approach that should take into account the efficacy (the ability of an intervention to get the desired result under ideal conditions), the effectiveness (the degree to which the intended effect is obtained under routine clinical practice conditions or settings) and the efficiency (value of the intervention as relative to its cost to the individual or society) of any therapeutic intervention. In a first step of the process, a group of 90 national experts from different areas of health-care and with a multidimensional and multidisciplinary perspective of the disease, defined the concepts of efficacy, effectiveness and efficiency of established therapeutic interventions within 7 key dimensions of the illness: symptomatology; comorbidity; relapse and adherence; insight and subjective experience; cognition; quality of life, autonomy and functional capacity; and social inclusion and associated factors. The main conclusions and recommendations of this stage of the work are presented herein.

Keywords: Adherence; Adherencia; Antipsicóticos; Antipsychotics; Conciencia de enfermedad; Insight; Negative symptoms; Psychosis; Síntomas negativos.

Publication types

  • Consensus Development Conference

MeSH terms

  • Antipsychotic Agents / therapeutic use
  • Combined Modality Therapy
  • Comorbidity
  • Efficiency
  • Humans
  • Patient Compliance
  • Personal Autonomy
  • Psychological Distance
  • Psychotherapy
  • Quality of Life
  • Recurrence
  • Schizophrenia / diagnosis
  • Schizophrenia / epidemiology
  • Schizophrenia / therapy*
  • Schizophrenic Psychology
  • Treatment Outcome

Substances

  • Antipsychotic Agents