Consideration of the ethnic prevalence of genotypes in the clinical use of tacrolimus

Pharmacogenomics. 2016 Nov;17(16):1737-1740. doi: 10.2217/pgs-2016-0136. Epub 2016 Oct 28.

Authors

Louise M Andrews¹, Brenda Cm De Winter¹, Teun Van Gelder^{1

2}, Dennis A Hesselink²

Affiliations

¹ Department of Hospital Pharmacy, Erasmus Medical Center, Room Na-206, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.
² Department of Internal Medicine, Nephrology & Transplantation, Erasmus Medical Center, Rotterdam, The Netherlands.

PMID: 27790923
DOI: 10.2217/pgs-2016-0136

No abstract available

Keywords: CYP3A5; ethnicity; tacrolimus; transplantation.

MeSH terms

Alleles
Cytochrome P-450 CYP3A / genetics*
Ethnicity / genetics
Humans
Immunosuppressive Agents / pharmacokinetics
Immunosuppressive Agents / therapeutic use*
Organ Transplantation*
Tacrolimus / pharmacokinetics
Tacrolimus / therapeutic use*

Substances

Immunosuppressive Agents
CYP3A5 protein, human
Cytochrome P-450 CYP3A
Tacrolimus