A controlled study on the anatomy of cervical extraforaminal ligaments and three-dimensional fast-imaging employing a steady-state acquisition sequence

Eur Spine J. 2017 Apr;26(4):1039-1046. doi: 10.1007/s00586-016-4823-7. Epub 2016 Nov 2.

Abstract

Purpose: To evaluate the utility of magnetic resonance three-dimensional fast-imaging employing a steady-state acquisition (MR 3D-FIESTA) sequence to study cervical EFLs using the anatomical results of cadavers as the gold standard.

Methods: Part I: The cervical regions of five embalmed adult cadavers were scanned using the MR 3D-FIESTA sequence. Ligamentous structures in the intervertebral foramina (IVFs) between C4 and T1 in the MRI scans were identified by a radiologist. Part II: After the specimens were scanned, gross and microscopic anatomical studies were conducted on the IVFs between C4 and T1 in the specimens by an anatomist. Part III: Using the anatomical results of the cadavers as the gold standard, the utility of the MR 3D-FIESTA sequence for imaging cervical EFLs was evaluated. Specificity, sensitivity, positive and negative predictive values (PPV and NPV, respectively) and accuracy were calculated.

Results: The occurrence rate of transforaminal ligaments (TFLs) in the IVFs between C4 and T1 was 42.5%. The results obtained by the radiologist using the MR 3D-FIESTA sequence to identify TFLs are as follows: specificity 96.2%, sensitivity 76.5%, PPV 92.9%, NPV 86.2%, and accuracy 88.4%.

Conclusion: MR 3D-FIESTA sequences clearly showed cervical EFLs. In the 3D-FIESTA sequence scans that the radiologist believed to indicate the presence of a cervical TFL, the probability that the TFL existed was approximately 93%. When the radiologist believed that no TFL was present in the 3D-FIESTA sequence scan, the probability that a TFL existed was 14%.

Keywords: Cervical vertebra; Extraforaminal ligament; MR 3D-FIESTA sequence; Transforaminal ligament.

MeSH terms

  • Adult
  • Aged
  • Cadaver
  • Cervical Vertebrae / anatomy & histology
  • Cervical Vertebrae / diagnostic imaging*
  • Congenital Abnormalities / diagnostic imaging*
  • Female
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Ligaments / abnormalities
  • Ligaments / anatomy & histology
  • Ligaments / diagnostic imaging*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Thoracic Vertebrae / anatomy & histology
  • Thoracic Vertebrae / diagnostic imaging*