Intracellular TG2 Activity Increases Microtubule Stability but is not Sufficient to Prompt Neurite Growth

Neurosci Bull. 2017 Feb;33(1):103-106. doi: 10.1007/s12264-016-0075-0. Epub 2016 Nov 4.

Authors

Shunling Guo¹, Brad A Palanski², Cornelius Kloeck², Chaitan Khosla^{2

3}, Bianxiao Cui⁴

Affiliations

¹ Department of Chemistry, Stanford University, Stanford, CA, 94305, USA. [email protected].
² Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
³ Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.
⁴ Department of Chemistry, Stanford University, Stanford, CA, 94305, USA. [email protected].

No abstract available

Publication types

Letter

MeSH terms

Amines / pharmacology
Animals
Biotin / analogs & derivatives
Biotin / pharmacology
Cell Differentiation / drug effects
Cells, Cultured
Cerebral Cortex / cytology
Dose-Response Relationship, Drug
Enzyme Inhibitors / pharmacology
GTP-Binding Proteins / metabolism*
Horses / blood
Humans
Microtubule-Associated Proteins
Microtubules / drug effects
Microtubules / metabolism*
Nerve Growth Factor / pharmacology
Neurites / drug effects*
Neurons / cytology*
Neurons / metabolism*
PC12 Cells
Protein Glutamine gamma Glutamyltransferase 2
Rats
Serum / metabolism
Time Factors
Transfection
Transglutaminases / metabolism*
tau Proteins / metabolism

Substances

Amines
Enzyme Inhibitors
Microtubule-Associated Proteins
Tgm2 protein, rat
tau Proteins
5-(biotinamido)pentylamine
Biotin
Nerve Growth Factor
Protein Glutamine gamma Glutamyltransferase 2
Transglutaminases
GTP-Binding Proteins

Grants and funding