Tc-99m TRODAT uptake in an osteoid tumor of clivus

Indian J Nucl Med. 2016 Oct-Dec;31(4):309-310. doi: 10.4103/0972-3919.190805.

Abstract

Tc-99m TRODAT is cocaine analog and binds to the dopamine transporter in vivo. Tc-99m TRODAT single-photon emission computed tomography/computed tomography. (SPECT/CT) is useful for demonstrating presynaptic dopaminergic dysfunction in patients with Parkinsonism. However, few reports have shown extrastriatal uptake of Tc-99m TRODAT. We present the case of a 67-year-old male who underwent Tc-99m TRODAT SPECT/CT for evaluation of Parkinsonism. In addition to tracer binding in the striatum, tracer uptake was noted in an osteoid tumor of the clivus. Integrated SPECT/CT enabled precise localization and characterization of the extrastriatal site of tracer binding and emphasizes the importance of such coincidental findings.

Keywords: Osteoid tumor; Parkinson's disease; Tc-99m TRODAT; single-photon emission computed tomography/computed tomography.