Abstract
Four patients treated with tricyclic antidepressants and one patient treated with trazodone all demonstrated marked increases in plasma levels of these drugs after the addition of fluoxetine. Such increases could increase adverse effects.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adult
-
Aged
-
Aged, 80 and over
-
Antidepressive Agents, Tricyclic / blood*
-
Chromatography, High Pressure Liquid
-
Drug Combinations
-
Female
-
Fluoxetine / pharmacology
-
Fluoxetine / therapeutic use*
-
Humans
-
Male
-
Trazodone / blood*
Substances
-
Antidepressive Agents, Tricyclic
-
Drug Combinations
-
Fluoxetine
-
Trazodone