School absenteeism among school-aged children with medically attended acute viral respiratory illness during three influenza seasons, 2012-2013 through 2014-2015

Influenza Other Respir Viruses. 2017 May;11(3):220-229. doi: 10.1111/irv.12440. Epub 2017 Feb 15.

Abstract

Background: Acute respiratory illnesses (ARIs) are common in school-aged children, but few studies have assessed school absenteeism due to specific respiratory viruses.

Objective: To evaluate school absenteeism among children with medically attended ARI due to common viruses.

Methods: We analyzed follow-up surveys from children seeking care for acute respiratory illness who were enrolled in the influenza vaccine effectiveness study at Marshfield Clinic during the 2012-2013 through 2014-2015 influenza seasons. Archived influenza-negative respiratory swabs were retested using multiplex RT-PCR to detect 16 respiratory virus targets. Negative binomial and logistic regression models were used to examine the association between school absence and type of respiratory viruses; endpoints included mean days absent from school and prolonged (>2 days) absence. We examined the association between influenza vaccination and school absence among children with RT-PCR-confirmed influenza.

Results: Among 1027 children, 2295 days of school were missed due to medically attended ARIs; influenza accounted for 39% of illness episodes and 47% of days missed. Mean days absent were highest for influenza (0.96-1.19) and lowest for coronavirus (0.62). Children with B/Yamagata infection were more likely to report prolonged absence than children with A/H1N1 or A/H3N2 infection [OR (95% CI): 2.1 (1.0, 4.5) and 1.7 (1.0, 2.9), respectively]. Among children with influenza, vaccination status was not associated with prolonged absence.

Conclusions: School absenteeism due to medically attended ARIs varies by viral infection. Influenza B infections accounted for the greatest burden of absenteeism.

Keywords: absenteeism; children; influenza.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Absenteeism*
  • Acute Disease / epidemiology
  • Acute Disease / psychology
  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Influenza A Virus, H1N1 Subtype / genetics
  • Influenza A Virus, H1N1 Subtype / immunology
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza A Virus, H3N2 Subtype / genetics
  • Influenza A Virus, H3N2 Subtype / immunology
  • Influenza A Virus, H3N2 Subtype / isolation & purification
  • Influenza Vaccines
  • Influenza, Human / epidemiology
  • Influenza, Human / psychology*
  • Influenza, Human / virology
  • Male
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / psychology*
  • Respiratory Tract Infections / virology
  • Schools / statistics & numerical data
  • Seasons
  • Students / psychology
  • Students / statistics & numerical data
  • Viruses / classification
  • Viruses / genetics
  • Viruses / immunology
  • Viruses / isolation & purification*
  • Wisconsin

Substances

  • Influenza Vaccines