Carbapenemase-Producing Enterobacteriaceae in Swine Production in the United States: Impact and Opportunities

Antimicrob Agents Chemother. 2017 Jan 24;61(2):e02348-16. doi: 10.1128/AAC.02348-16. Print 2017 Feb.

Abstract

The discovery of carbapenemase-producing Enterobacteriaceae in U.S. swine production is troubling and underscores a tumultuous period where the outlook on the battle against superbugs is bleak. However, all is not lost. This commentary highlights both the good and the bad that can come from such findings, including those of a recent study published by Mollenkopf et al. (Antimicrob Agents Chemother 61:e012198-16, 2017, https://doi.org/doi:10.1128/AAC.01298-16).

Keywords: antibiotic resistance; carbapenems; superbug; swine.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / metabolism*
  • Drug Resistance, Bacterial / genetics
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / genetics
  • Swine
  • United States
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase