Abstract
The resurgence of invasive meningococcal disease caused by Neisseria meningitidis serogroup W with sequence type ST-11 (cc11) was observed in Madagascar in 2015-2016. Three cases were investigated in this study. Molecular characterization of the strains suggests the local transmission of a single genotype that may have been circulating for years.
Keywords:
Madagascar; Neisseria meningitidis; Serogroup W; Whole genome sequencing (WGS).
Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
MeSH terms
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Adult
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Anti-Bacterial Agents / administration & dosage
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Antibiotic Prophylaxis / methods
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Bacterial Typing Techniques
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Cephalosporins / administration & dosage
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Ciprofloxacin / administration & dosage
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Disease Outbreaks
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Female
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Genotype
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Humans
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Incidence
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Infant
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Madagascar / epidemiology
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Male
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Meningococcal Infections / drug therapy
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Meningococcal Infections / epidemiology*
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Meningococcal Infections / microbiology*
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Molecular Epidemiology
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Neisseria meningitidis / classification*
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Neisseria meningitidis / genetics
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Neisseria meningitidis / isolation & purification*
Substances
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Anti-Bacterial Agents
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Cephalosporins
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Ciprofloxacin