NCCN Guidelines Insights: Chronic Myeloid Leukemia, Version 1.2017

J Natl Compr Canc Netw. 2016 Dec;14(12):1505-1512. doi: 10.6004/jnccn.2016.0162.

Abstract

The NCCN Guidelines for Chronic Myeloid Leukemia (CML) provide recommendations for the management of chronic-phase and advanced-phase CML in adult patients. The median age of disease onset is 67 years. However, because CML occurs in all age groups, clinical care teams should be prepared to address issues relating to fertility and pregnancy with patients who are of reproductive age at the time of diagnosis. CML is relatively rare in children and there are no evidence-based recommendations for the management of CML in pediatric population. These NCCN Guidelines Insights discuss special considerations for the management of CML during pregnancy and for the management of CML in the pediatric population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Drug-Induced / epidemiology*
  • Adult
  • Aged
  • Child
  • Evidence-Based Medicine / standards
  • Female
  • Fertility / drug effects*
  • Humans
  • Leukemia, Myeloid, Chronic-Phase / drug therapy*
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Complications, Neoplastic / drug therapy*
  • Prognosis
  • Protein Kinase Inhibitors / administration & dosage
  • Protein Kinase Inhibitors / adverse effects*
  • Protein Kinase Inhibitors / therapeutic use*
  • Withholding Treatment

Substances

  • Protein Kinase Inhibitors