Case 37-2016. An 86-Year-Old Woman with Leukocytosis and Splenomegaly

N Engl J Med. 2016 Dec 8;375(23):2273-2282. doi: 10.1056/NEJMcpc1509539.

Authors

Amir T Fathi¹, Timothy A Graubert¹, Naveen M Kulkarni¹, Frank C Kuo¹, Robert P Hasserjian¹

Affiliation

¹ From the Departments of Medicine (A.T.F., T.A.G.), Radiology (N.M.K.), and Pathology (R.P.H.), Massachusetts General Hospital, the Department of Pathology, Brigham and Women's Hospital (F.C.K.), and the Departments of Medicine (A.T.F., T.A.G.), Radiology (N.M.K.), and Pathology (F.C.K., R.P.H.), Harvard Medical School - all in Boston.

PMID: 27959687
DOI: 10.1056/NEJMcpc1509539

No abstract available

Publication types

Case Reports
Clinical Conference

MeSH terms

Aged, 80 and over
Blood Cells / pathology
Bone Marrow / pathology*
Diagnosis, Differential
Fatigue / etiology
Female
Humans
Leukemia, Neutrophilic, Chronic / complications
Leukemia, Neutrophilic, Chronic / genetics
Leukemia, Neutrophilic, Chronic / pathology*
Leukocytosis / etiology*
Mutation
Neutrophils
Receptors, Colony-Stimulating Factor / genetics*
Splenomegaly / etiology
Sweating

Substances

CSF3R protein, human
Receptors, Colony-Stimulating Factor