Effect of MTA particle size on periapical healing

Int Endod J. 2017 Dec:50 Suppl 2:e3-e8. doi: 10.1111/iej.12738. Epub 2017 Feb 9.

Abstract

Aim: To examine the effect of reduction in MTA particle size on dento-alveolar and osseous healing in dogs.

Methodology: Root canals of 24 mandibular premolars in four 2-year-old beagles were prepared and filled with gutta-percha and sealer. Two to four weeks later, during periapical surgery, the root-end cavity preparations in these teeth were filled with either grey ProRoot MTA or modified (reduced particle sizes with faster setting time) MTA. The animals were sacrificed 4 months later. Degrees of inflammation, type of inflammatory cells, fibrous connective tissue adjacent to the root-end filling materials, cementum formation over the resected roots and root-end filling materials and bone healing were examined. Data were analysed using the McNemar test.

Results: No significant differences in healing of periapical tissues were found when comparing ProRoot MTA to a modified MTA containing reduced particle sizes.

Conclusion: Reducing the particle sizes of MTA did not impact its biological properties.

Keywords: MTA; fast-set; periapical healing; root-end filling material.

MeSH terms

  • Aluminum Compounds / pharmacology*
  • Animals
  • Bicuspid / surgery
  • Calcium Compounds / pharmacology*
  • Dogs
  • Drug Combinations
  • Gutta-Percha / pharmacology
  • Mandible
  • Oxides / pharmacology*
  • Particle Size
  • Periapical Tissue / drug effects*
  • Root Canal Filling Materials / pharmacology*
  • Root Canal Therapy*
  • Silicates / pharmacology*
  • Wound Healing / drug effects*

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Drug Combinations
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • mineral trioxide aggregate
  • Gutta-Percha