The correlation between EDSS and cognitive impairment in MS patients. Assessment of a Brazilian population using a BICAMS version

Arq Neuropsiquiatr. 2016 Dec;74(12):974-981. doi: 10.1590/0004-282X20160151.

Abstract

Objectives: To investigate the correlation between the disabilities of MS patients and their cognitive impairment assessed by the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS).

Methods: Forty patients with definitive diagnoses of MS were selected. The correlation coefficient (r) between the Expanded Disability Status Scale (EDSS) and the neuropsychological tests of BICAMS were calculated.

Results: The correlation was clinically substantial and significant with r = 0.55 (p < 0.01) in the Symbol Digit Modalities Test (SDMT), 0.54 (p < 0.01) in the Brief Visuospacial Memory Test (BVMT) and 0.40 (p < 0.05) in the California Verbal Learning Test (CVLT).

Conclusion: BICAMS has easy and satisfactory application and evaluation for routine visits and presents a significant correlation with the EDSS. Its use may be indicated for screening and monitoring of cognitive impairment in patients with MS.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Brazil
  • Brief Psychiatric Rating Scale / standards*
  • Cognition Disorders / diagnosis
  • Cognition Disorders / psychology*
  • Disability Evaluation*
  • Educational Status
  • Female
  • Humans
  • Language
  • Male
  • Middle Aged
  • Multiple Sclerosis, Relapsing-Remitting / diagnosis
  • Multiple Sclerosis, Relapsing-Remitting / psychology*
  • Neuropsychological Tests / standards
  • Young Adult