Comparison of Anterior Segment Measurements with Optical Low-coherence Reflectometry and Partial-coherence Interferometry Optical Biometers

Middle East Afr J Ophthalmol. 2016 Oct-Dec;23(4):288-292. doi: 10.4103/0974-9233.194075.

Abstract

Aims: To evaluate a new noncontact optical biometer using partial-coherence interferometry and to compare the clinical measurements with those obtained from the device using optical low-coherence reflectometry (OLCR).

Setting and design: Ondokuz Mayis University, Samsun, Turkey. Nonrandomized, prospective clinical trial.

Subjects and methods: The study was performed on the healthy phakic eyes of volunteers in the year 2014. Measurements of axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT), mean keratometry (K), and white-to-white (WTW) measurements obtained with the low-time coherence interferometry (LTCI) were compared with those obtained with the OLCR.

Statistical analysis used: The results were evaluated using Bland-Altman analyses. The differences between both methods were assessed using the paired t-test, and its correlation was evaluated by Pearson's coefficient.

Results: We examined seventy participants with a mean age of 33.06 (±9.7) (range: 19-53) years. AL measurements with LTCI and OLCR were 23.7 (±1.08) mm and 23.7 (±1.1) mm, respectively. ACD was 3.6 (±0.4) mm and 3.5 (±0.4) mm for LTCI and OLCR, respectively. The mean CCT measurements for both devices were 533 (±28) mm and 522 (±28) mm, respectively. The mean K readings measurements for LTCI and OLCR were 43.3 (±1.5) D and 43.3 (±1.5) D, respectively. The mean WTW distance measurements for both devices were 12.0 (±0.5) mm and 12.1 (±0.5) mm, respectively.

Conclusions: Measurements with LTCI correlated well with those with the OLCR. These two devices showed good agreement for the measurement of all parameters.

Keywords: Axial Length; Low Time Coherence Interferometry; Optical Biometer; Optical Low-Coherence Reflectometry.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Anterior Eye Segment / anatomy & histology*
  • Axial Length, Eye / anatomy & histology
  • Biometry / methods
  • Cornea / anatomy & histology
  • Corneal Pachymetry
  • Female
  • Healthy Volunteers
  • Humans
  • Interferometry / methods*
  • Male
  • Middle Aged
  • Prospective Studies
  • Reproducibility of Results
  • Tomography, Optical Coherence / methods*
  • Young Adult