Exacerbations and health care resource utilization in patients with airflow limitation diseases attending a primary care setting: the PUMA study

Int J Chron Obstruct Pulmon Dis. 2016 Dec 7:11:3059-3067. doi: 10.2147/COPD.S120776. eCollection 2016.

Abstract

Background: COPD, asthma, and asthma-COPD overlap increase health care resource consumption, predominantly because of hospitalization for exacerbations and also increased visits to general practitioners (GPs) or specialists. Little information is available regarding this in the primary care setting.

Objectives: To describe the prevalence and number of GP and specialist visits for any cause or due to exacerbations in patients with COPD, asthma, and asthma-COPD overlap.

Methods: COPD was defined as post-bronchodilator forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) ratio <0.70; asthma was defined as prior medical diagnosis, wheezing in the last 12 months, or wheezing plus reversibility (post-bronchodilator FEV1 or FVC increase ≥200 mL and ≥12%); asthma-COPD overlap was defined as post-bronchodilator FEV1/FVC <0.70 plus prior asthma diagnosis. Health care utilization was evaluated as GP and/or specialist visits in the previous year.

Results: Among the 1,743 individuals who completed the questionnaire, 1,540 performed acceptable spirometry. COPD patients had a higher prevalence of any medical visits to any physician versus those without COPD (37.2% vs 21.8%, respectively) and exacerbations doubled the number of visits. The prevalence of any medical visits to any physician was also higher in asthma patients versus those without asthma (wheezing: 47.2% vs 22.7%; medical diagnosis: 54.6% vs 21.6%; wheezing plus reversibility: 46.2% vs 23.8%, respectively). Asthma patients with exacerbations had twice the number of visits versus those without an exacerbation. The number of visits was higher (2.8 times) in asthma-COPD overlap, asthma (1.9 times), or COPD (1.4 times) patients versus those without these respiratory diseases; the number of visits due to exacerbation was also higher (4.9 times) in asthma-COPD overlap, asthma (3.5 times), and COPD (3.8 times) patients.

Conclusion: COPD, asthma, and asthma-COPD overlap increase the prevalence of medical visits and, therefore, health care resource utilization. Attempts to reduce health care resource use in these patients require interventions aimed at preventing exacerbations.

Keywords: COPD; PUMA; asthma; asthma-COPD overlap; exacerbation; health care resource utilization; primary care.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adult
  • Airway Obstruction / diagnosis
  • Airway Obstruction / physiopathology
  • Airway Obstruction / therapy*
  • Asthma / diagnosis
  • Asthma / physiopathology
  • Asthma / therapy*
  • Cross-Sectional Studies
  • Disease Progression
  • Female
  • Forced Expiratory Volume
  • General Practice
  • Health Resources / statistics & numerical data*
  • Humans
  • Lung / physiopathology*
  • Male
  • Middle Aged
  • Office Visits / statistics & numerical data
  • Phenotype
  • Predictive Value of Tests
  • Primary Health Care / statistics & numerical data*
  • Pulmonary Disease, Chronic Obstructive / diagnosis
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / therapy*
  • Referral and Consultation / statistics & numerical data
  • Risk Factors
  • Severity of Illness Index
  • South America
  • Spirometry / statistics & numerical data
  • Surveys and Questionnaires / statistics & numerical data
  • Syndrome
  • Time Factors
  • Treatment Outcome
  • Vital Capacity