Serotypes not Included in 13-Valent Pneumococcal Vaccine as Causes of Acute Otitis Media with Spontaneous Tympanic Membrane Perforation in a Geographic Area with High Vaccination Coverage

Pediatr Infect Dis J. 2017 May;36(5):521-523. doi: 10.1097/INF.0000000000001485.

Abstract

In 177 children living in an area with high 13-valent pneumococcal conjugate vaccine 13 coverage, who had acute otitis media complicated with spontaneous tympanic membrane perforation, Streptococcus pneumoniae was identified in the middle ear fluid of 48 (27.1%) subjects, with 37 (77.1%) cases caused by nonpneumococcal conjugate vaccine 13 serotypes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child, Preschool
  • Exudates and Transudates / microbiology
  • Female
  • Humans
  • Infant
  • Male
  • Otitis Media / complications
  • Otitis Media / microbiology*
  • Pneumococcal Infections / microbiology*
  • Pneumococcal Vaccines / immunology*
  • Serogroup*
  • Streptococcus pneumoniae / classification*
  • Streptococcus pneumoniae / isolation & purification*
  • Tympanic Membrane Perforation / microbiology*

Substances

  • 13-valent pneumococcal vaccine
  • Pneumococcal Vaccines