Precursor-directed in situ synthesis of Saccharothriolides G and H by the Actinomycete Saccharothrix sp. A1506

J Antibiot (Tokyo). 2017 May;70(5):718-720. doi: 10.1038/ja.2016.153. Epub 2016 Dec 21.

Authors

Shan Lu¹, Shinichi Nishimura¹, Masashi Ito², Taira Kato², Hideaki Kakeya¹

Affiliations

¹ Division of Bioinformatics and Chemical Genomics, Department of System Chemotherapy and Molecular Sciences, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
² Bioresource Laboratories, MicroBioPharm Japan Co Ltd (MBJ), Shizuoka, Japan.

PMID: 27999442
DOI: 10.1038/ja.2016.153

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Actinobacteria / metabolism*
Antineoplastic Agents / chemistry
Antineoplastic Agents / isolation & purification
Antineoplastic Agents / metabolism*
Antineoplastic Agents / pharmacology
Cell Line, Tumor
Humans
Macrolides / chemistry
Macrolides / isolation & purification
Macrolides / metabolism*
Macrolides / pharmacology
Secondary Metabolism

Substances

Antineoplastic Agents
Macrolides