Tumescent Anesthesia in Skin- and Nipple-sparing Mastectomy: Results of a Prospective Clinical Study

Anticancer Res. 2017 Jan;37(1):349-352. doi: 10.21873/anticanres.11328.

Abstract

Background: The tumescent mastectomy technique has been used to facilitate dissection of subcutaneous tissue and mammary gland in order to reduce intraoperative bleeding and speed the operation.

Patients and methods: A prospective clinical study was performed on 30 female patients undergoing immediate breast reconstructions after skin-sparing mastectomy (SSM) or nipple-sparing mastectomy (NSM) in order to assess early postoperative complications, pain, and final esthetic outcome of skin flaps related to tumescent anesthesia (TA).

Results: TA significantly speeded-up the operative procedure (131±49.99 vs. 180.5±67.15 min; p=0.03) achieving less skin damage compared to patients who did not have TA (p=0.045); moreover, no significant difference occurred with regard to the length of in-hospital stay and overall lymphatic drainage.

Conclusion: The length of the operation as well as the final cosmetic outcome of skin flaps was significantly improved due to TA, with no appreciable side-effects.

Keywords: Breast cancer; breast reconstruction; tumescent anesthesia.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Anesthesia / methods*
  • Breast Neoplasms / surgery
  • Epinephrine / therapeutic use
  • Female
  • Hospitalization
  • Humans
  • Mammaplasty / methods
  • Mastectomy / methods*
  • Middle Aged
  • Nipples / surgery
  • Operative Time
  • Pain, Postoperative
  • Skin
  • Surgical Flaps

Substances

  • Epinephrine