Background: Up to now, the feasibility and benefit of using fluorescein sodium under a dedicated surgical microscope filter (YE560, YELLOW 560 nm filter, Carl Zeiss Meditec, Germany) has never been clinically evaluated in infectious disorders of the brain.
Case description: Here, we report the case of a male patient with a brain abscess in the right parietal lobe that was removed under fluorescence-guidance (intravenous administration of fluorescein sodium 10%, 5 mg/kg bodyweight). The abscess capsule showed intensive yellow fluorescent staining, while - under white light - the cortex appeared normal.
Conclusion: This technique may improve the identification and surgical removal of brain abscesses.
Keywords: Blood–brain barrier; YELLOW 560 nm filter; brain abscess; fluorescein sodium; fluorescence-guided surgery.