Treatment of Sweat gland carcinoma with Topical Aminolevulinic Acid Photodynamic therapy: An effective treatment method to improve surgical outcomes

Photodiagnosis Photodyn Ther. 2017 Mar:17:233-235. doi: 10.1016/j.pdpdt.2016.12.004. Epub 2016 Dec 27.

Abstract

Background: Sweat gland carcinoma is an extremely rare skin cancer, which is hard to diagnose and completely resect without causing functional and cosmetic problems. Moreover, the high rate of recurrence is hard to handle in the treatment of sweat gland carcinoma. Photodynamic therapy is a novel treatment protocol which can selectively destroy tumor cells with good functional and cosmetic outcomes.

Methods: This is a case about a 53 years old patient with sweat gland carcinoma on his right foot, which received surgery and photodynamic therapy.

Results: There is no recurrence one year after treatment of surgery and photodynamic therapy.

Conclusions: Excision combined with photodynamic therapy during operation is a promising strategy towards tumors which are hard to resect thoroughly and have a high risk of recurrence.

Keywords: Aminolevulinic acid; Efficacy; Surgery; Sweat gland carcinoma; Topical photodynamic therapy.

Publication types

  • Case Reports

MeSH terms

  • Aminolevulinic Acid / therapeutic use*
  • Foot
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use*
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Sweat Glands / pathology*
  • Sweat Glands / surgery

Substances

  • Photosensitizing Agents
  • Aminolevulinic Acid