Parasympathetic baroreflexes and heart rate variability during acute stage of sport concussion recovery

Brain Inj. 2017;31(2):247-259. doi: 10.1080/02699052.2016.1226385. Epub 2017 Jan 3.

Abstract

Primary objective: To assess and compare the parasympathetic state of individuals in healthy vs concussion groups, by measuring cardiovascular metrics under resting and baroreflex conditions using a squat-stand manoeuvre.

Research design: This was a retrospective mixed-method study, with participants who sustained a medically diagnosed sport concussion (n = 12), being tested within 72-hours post-injury.

Methods and procedures: Participant's heart rate (Electrocardiogram, ECG) and blood pressure (finger plethysmography) data was collected during rest and during 10-second squat-stands (10SS, 0.05 Hz). Blood pressure and heart rate standard deviation data was analysed in the 0-5 seconds and 6-10 seconds periods of squatting and standing. Resting and baroreflex ECG data were analysed via Fourier Transformations for %Low Frequency and %High Frequency (%LF and %HF).

Results: The control group alleviated more pressure and had a significantly higher standard deviation of heart rate during the 6-10 seconds of squatting (p < 0.05). Overall heart rate standard deviation in the concussion group was significantly lower than healthy controls when standing (p < 0.05). There were no differences in %LF and % HF between groups or between rest and 10SS.

Conclusion: This study provides preliminary evidence that autonomic function is dysregulated following mTBI within the initial 72 hours of injury.

Keywords: Concussion; autonomic nervous system; baroreflexes; heart rate variability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Athletic Injuries / physiopathology*
  • Baroreflex / physiology*
  • Blood Pressure / physiology
  • Brain Concussion / physiopathology*
  • Electrocardiography
  • Female
  • Heart Rate / physiology*
  • Humans
  • Male
  • Parasympathetic Nervous System / physiopathology*
  • Retrospective Studies
  • Young Adult

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