In spite of its elimination from Tunisia, malaria remains a public health concern due to the severity of the disease and risk of its reintroduction. The vulnerability of our country is related to the persistent anophelism and to the existence of a potential reservoir represented by imported cases. In the absence of a stay in an endemic area, the suspicion of malaria remains a rare event. However, in front of the possibility of other modes of contamination, this parasitosis must be evoked in any fever without obvious etiology. Especially as delayed diagnosis in non immune subjects may cause a severe illness and death. We propose to present the principal clinical and biological aspects of malaria and to specify the action to be taken when the infection is contracted outside a stay in endemic areas, in order to determine the origin of contamination.