New pieces to an old puzzle: identifying the warfarin-binding site that prevents clotting

Nat Struct Mol Biol. 2017 Jan 5;24(1):5-6. doi: 10.1038/nsmb.3356.
No abstract available

MeSH terms

  • Anticoagulants / chemistry
  • Anticoagulants / metabolism*
  • Binding Sites
  • Blood Coagulation / drug effects*
  • Models, Molecular
  • Protein Binding
  • Protein Conformation
  • Vitamin K Epoxide Reductases / antagonists & inhibitors*
  • Vitamin K Epoxide Reductases / chemistry
  • Warfarin / chemistry
  • Warfarin / metabolism*

Substances

  • Anticoagulants
  • Warfarin
  • Vitamin K Epoxide Reductases