[CT findings of inflammatory myofibroblastic tumor of different pathological types]

Zhonghua Yi Xue Za Zhi. 2017 Jan 3;97(1):43-46. doi: 10.3760/cma.j.issn.0376-2491.2017.01.011.
[Article in Chinese]

Abstract

Objective: To explore the computed tomography(CT) features of inflammatory myofibroblastic tumor(IMT) in different pathological types, and improve the diagnostic level of this disease. Methods: The CT features of 29 cases pathologically confirmed IMTs were retrospectively reviewed along with a literature review to analyze the CT features and pathological correlations, and three kinds of pathological classification of IMT in patients with gender , shape, boundary and location were respectively analyzed by Chi-Square test. Results: The age ranges from 2 to 78 years.There were 7 cases of mucinous blood vessel type and 13 cases of spindle cell type and 9 cases of fiber type.Immunohistochemically, Vimentin (22/29) and SMA (28/29) were positive in all the cases, ALK (4/29) and CD-67(6/29) were partly positive expression, other markers such as S-100 were negative expression.The Chi-Square test showed that there were statistically differences in the gender of the patients. Conclusion: The CT and clinical features differ according to pathological types of IMT. Its final diagnosis still needs to be combined with pathology and immunohistochemistry result. In all, CT has a role in assessing the extension of IMT and especially about the relationship with adjacent organs which can effectively direct the establishment of clinical treating scheme.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Granuloma, Plasma Cell*
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Neoplasms
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Vimentin
  • Young Adult

Substances

  • Vimentin