[Biosimilars in Inflammatory Bowel Disease (IBD): Experiences and perceptions of german gastroenterologists]

Z Gastroenterol. 2017 Apr;55(4):369-374. doi: 10.1055/s-0042-121520. Epub 2017 Jan 5.
[Article in German]

Abstract

The European Medicines Agency (EMA) recently approved the first anti-TNF-alpha biosimilar for infliximab (CT-P13) (trade names: Inflectra® and Remsima®) in Germany. Over the past year, German gastroenterologists gained experience treating IBD-patients with infliximab biosimilars (IFX-biosimilars). To evaluate their experiences and opinions on biosimilars, we conducted a nationwide online survey among German gastroenterologists. Our results are based on the assessment of 449 questionnaires. Although 61 % of the participants had already prescribed IFX-biosimilars, about two thirds of these participating gastroenterologists with IFX-biosimilar prescription stated their experience as based on fewer than 10 IBD-patients treated with IFX-biosimilars. Only 15 % considered themselves to be very experienced with biosimilars. The lower price in comparison to the originator is seen as the most important advantage of biosimilars (71 %). More than two thirds of the survey participants requested specific gastroenterological trials and registries to increase the data available on biosimilars in IBD-patients (68 %).

MeSH terms

  • Biosimilar Pharmaceuticals / therapeutic use*
  • Gastroenterologists*
  • Gastrointestinal Agents / therapeutic use*
  • Germany
  • Humans
  • Inflammatory Bowel Diseases / drug therapy*
  • Inflammatory Bowel Diseases / therapy*
  • Infliximab / therapeutic use*
  • Practice Patterns, Physicians'*
  • Prescriptions
  • Surveys and Questionnaires
  • Tumor Necrosis Factor-alpha

Substances

  • Biosimilar Pharmaceuticals
  • Gastrointestinal Agents
  • Tumor Necrosis Factor-alpha
  • Infliximab