Atopic keratoconjunctivitis: long-term results of medical treatment and penetrating keratoplasty

Arq Bras Oftalmol. 2016 Nov-Dec;79(6):376-379. doi: 10.5935/0004-2749.20160107.

Abstract

Purpose:: To evaluate the long-term outcomes of medically or surgically treated patients with atopic keratoconjunctivitis (AKC).

Methods:: Charts of 16 patients with AKC (32 eyes) observed between 1996 and 2013 were reviewed retrospectively. Outcome measures included demographic features, follow-up duration, and biomicroscopic findings at the first and most recent visits. The corrected distance visual acuity (CDVA; in decimal units) was evaluated at the initial visit and the 1-, 6-, and 12-month follow-up visits.

Results:: In the medically treated group (25 eyes of 15 patients), the median follow-up duration was 3 (range, 1-9) years, and the median CDVA values were 0.01 (0.001-1.0) at the first visit and 0.01 (0.001-0.8) at the most recent visit (p=0.916). In the penetrating keratoplasty (PK) group (7 eyes of 6 patients), the median follow-up duration was 7 years (range, 1-11), and the median CDVA increased from 0.01 (0.001-0.01) to 0.2 (0.001-0.7) postoperatively (p=0.043).

Conclusion:: Whereas most AKC patients maintained a useful CDVA with medical treatment, PK may be required in some cases. Despite the frequent occurrence of complications, PK can significantly improve the CDVA.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Case-Control Studies
  • Conjunctivitis, Allergic / surgery
  • Conjunctivitis, Allergic / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Keratoconjunctivitis / surgery
  • Keratoconjunctivitis / therapy*
  • Keratoplasty, Penetrating*
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity / physiology*
  • Young Adult