The thalamus as a relay station and gatekeeper: relevance to brain disorders

Rev Neurosci. 2017 Feb 1;28(2):203-218. doi: 10.1515/revneuro-2016-0067.

Abstract

Here, we provide a review of behavioural, cognitive, and neural studies of the thalamus, including its role in attention, consciousness, sleep, and motor processes. We further discuss neuropsychological and brain disorders associated with thalamus function, including Parkinson's disease, Alzheimer's disease, Korsakoff's syndrome, and sleep disorders. Importantly, we highlight how thalamus-related processes and disorders can be explained by the role of the thalamus as a relay station.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / physiopathology*
  • Animals
  • Brain / physiopathology*
  • Humans
  • Nerve Net / physiopathology*
  • Neuropsychological Tests
  • Parkinson Disease / physiopathology
  • Thalamus / physiopathology*